Mesothelioma Epidemiology
If the association of malignant tumors,mesotheliomas with radiotherapy or zeolite exposure,severe pulmonary disease,recurrent diverticulitis,even if lipid aspiration pneumonia were reported,Asbestos remains the most common etiological cause of documented contact with approximately half of all patients with primary malignancies of the pleura and peritoneum. Although only one of the first 13 cases of Malignant Mesothelioma of the testis in the literature of the persons exposed Asbestos,3 of the 4 most recently reported cases were very vulnerable. To date,asbestos does not appear to be involved in the etiology of Benign Mesothelioma any or primary malignant pericardial tumors.
Association of asbestos and the excess risk of lung cancer was Founded in 1955,Doll,although case reports first appeared in 1935.
The role of asbestos in the etiology of mesothelioma was demonstrated convincingly Wagner et al. 1960th They found that 45 out of 47 South African patients with this rare malignancy previously had a history of contact with asbestos. Special emphasis was that most patients are not minor asbestos but had lived and worked in areas where asbestos was used.
The percentage of patients with mesothelioma with a history of contact with asbestos can be obtained in the range from zero to 80-90% in many coastal areas of the United Transport Company States and England,and South Africa and the Canadian mining area. Some patients without a history of contact with asbestos can be long Exposure forgotten or mysterious. Asbestos bodies are often found at autopsy in individuals in the general population. However,in the absence asbestos in the body of a careful examination of lung tissue taken at autopsy from patients with mesothelioma without contact with asbestos supports known that significant exposure to asbestos. asbestos bodies,also called ferruginous bodies are hemosiderin cores and the coated fiber-glycoprotein. While other organic and inorganic fibers can produce ferruginous bodies,those found in the lungs of human nuclei were more asbestos. uncoated fibers in the lungs,are much more numerous ferruginous bodies visible.
Since 1960,epidemiologists estimated the number of reputable,mainly due to carefully designed case-control study,the risk of cancer associated with asbestos. The risk of mesothelioma among highly exposed individuals is estimated to be as high as 7-10'rv different studies.
Peritoneal Mesothelioma good proportion of the pleura in some cohort of workers heavily exposed to asbestos is approximately 3:2,Global Report 2:05 ET observed in most series,probably because a larger number of people exposed temporarily.
Striking with a long latency period for developing mesothelioma. Although several cases were reported 20 years or less after the first exposure,the peak incidence of disease occurs after 35-45 years.